Adiponectin in Cattle: Profiling of molecular weight patterns in different body fluids at different physiological states and assessment of adiponectin¿s effects on lymphocytes

Heinz, Johanna

Omschrijving

Adiponectin (AdipoQ), one of the most abundant adipokines found in circulation exerts various metabolic functions. It is negatively correlated with body fat content and is known to be a key regulator of insulin sensitivity and tissue inflammation. Different molecular weight (MW) forms of AdipoQ are found in circulation: a low molecular weight (LMW) trimer, a middle molecular weight (MMW) hexamer and a high molecular weight (HMW) form which is built of 12 to 18 monomers. Cattle are used for milk and meat production and contribute greatly to the human food supply. Dairy cows undergo various metabolic changes in the time from late pregnancy to early lactation. This causes a mobilization of body reserves which may lead to a higher risk for infectious diseases and possible problems in fertility later. The aims of this thesis were estimated the molecular weight pattern of AdipoQ in several body fluids e.g. serum, milk, follicular fluid and seminal plasma of cows and bulls. Additionally the potential influences of AdipoQ on lymphocyte function were estimated.
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Schrijver
Heinz, Johanna
Titel
Adiponectin in Cattle: Profiling of molecular weight patterns in different body fluids at different physiological states and assessment of adiponectin¿s effects on lymphocytes
Uitgever
Jentzsch-Cuvillier, Annette
Jaar
2015
Taal
Engels
Pagina's
136
Gewicht
185 gr
EAN
9783954047475
Afmetingen
211 x 146 x 11 mm
Bindwijze
Paperback

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